Combino AI

Nearly 66 percent of us take at least one prescribed drug; for many (mainly elderly) it amounts to a fistful, potpourri of pills per day. Meanwhile, new drug approvals have reached a 19-year high. It’s a mark cheered notably for the swift minting of medications to tackle  “orphan diseases” and new infectious disease emergencies. However, death by prescription has become one of medicine's major current problems, as there is still a delay in understanding the relationships between substances, effects and diseases and a difficulty in dealing with so many pharmaceutics at the same time. Combino is the intelligent system capable of accelerating the discovery and suspicion of drugs for diseases. On a global scale, it can exponentially increase the speed of pharmaceutical research.

About 328,000 patients in the U.S. and Europe die from prescription drugs each year. This makes prescription drugs a major health risk, ranking 4th with stroke as a leading cause of death. In places with poor hospital conditions and in contexts of overcrowding of hospital capacity (such as in emergencies of infectious diseases), this number tends to be even bigger.

A doctor on a working day attends and prescribes for dozens of patients with the most diverse diseases and, very often, that same patient is taking other medications that concern other specialties of medicine. The patient does not always remember or know all the information about the medications he is taking and that doctor will probably spend some time researching the drug that is not used in his medical specialty.

Besides that, with the fast emergence of new diseases and the massive approval of new pharmaceutical products, it is humanly difficult and time-consuming to recognize relationships between substances, effects and diseases. New prescription drugs have a 1 in 5 chance of causing serious reactions after being approved and the confirmation that a new disease can be treated or not with a certain substance takes a long time.

Combino is a smart platform that streamlines and helps healthcare in hospitals.

When a doctor is going to prescribe a drug, the system automatically corresponds with alerts, indications and suggestions for that drug due to the patient's profile or due to a "suspicion" of the program.

Through statistics and machine learning, the program is able to create "suspicions": Whether a particular drug has an influence or not on a new disease; Remedies having problems when combined; A certain drug is not recommended for a class of patients.

These "suspicions" will be constantly updated and open to the public, in order to direct and assist further research on medicines to be done.

Besides that, all people can make and update their personal data at any time via the web, providing basic information and information about their remedies and current illnesses. This information will be added to a unique profile of the Combino system, which also has the patient's history at the hospitals integrated into the system. Combino also uses databases with pharmaceutical substances with their usage information and interactions with other drugs.

The platform will instantly help doctors with the proper medical prescription, reducing possible medical errors and streamlining medical conduct (without the need for manual internet research or consulting the patient record).

In addition, the intelligent system can alert suspected drugs and drug combinations that may have some bad effect (due to the incidence of cases in the database), helping scientists to direct their research in the face of emergency situations (this tool could have helped and accelerated the identification of ibuprofen as a contraindication in the COVID-19 pandemic, for example) or new prescription drugs (decreasing the risk of drugs causing serious reactions after they have been approved).

The main patients to be helped with this system are those with continuous use of many medicines and those with new or little known diseases in the health area. The platform must reduce the mortality rate due to erroneous medical prescription and also improve the quality of life of users of drugs with side effects.

Combino is a platform that constantly tries to track relationships between drugs, effects and diseases. In the beginning of epidemics, for example, it takes time to understand which remedies can and cannot be used for treatment. The program with data information is able to raise suspicions about the effects of a medicine more quickly than a human, directing research and reducing the time for creating new treatments. Also, this tool helps to quickly prescribe a medicine, which can increase the productivity of doctors. Finally, Combino should decrease the number of hospitalized by prescribed drugs (about 1.9 million hospitalizations/year in US).